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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCM3 All Species: 52.42
Human Site: T368 Identified Species: 82.38
UniProt: P25205 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P25205 NP_002379.2 808 90981 T368 T A P R A I P T T G R G S S G
Chimpanzee Pan troglodytes XP_001151750 808 90957 T368 T A P R A I P T T G R G S S G
Rhesus Macaque Macaca mulatta XP_001106966 808 90990 T368 T A P R A I P T T G R G S S G
Dog Lupus familis XP_538960 916 102667 T476 T A P R A I P T T G R G S S G
Cat Felis silvestris
Mouse Mus musculus P25206 812 91528 T368 T A P R A I P T T G R G S S G
Rat Rattus norvegicus XP_001070728 813 91641 T368 T A P R A I P T T G R G S S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZMN2 812 91233 T369 T A P R A V G T T G R G S S G
Frog Xenopus laevis Q7ZXZ0 806 90528 T368 T A P R A I P T T G R G S S G
Zebra Danio Brachydanio rerio NP_997732 807 90502 T367 T A P R A I P T T G R G S S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_511048 819 90900 T363 T A P R A I P T T G R G S S G
Honey Bee Apis mellifera XP_625020 811 91329 T365 T A P R A I P T T G R G S S G
Nematode Worm Caenorhab. elegans Q21902 759 84917 P340 L I A K S I A P S I Y G S A D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays Q43704 768 85163 Q348 D P S V A K S Q L L R A V M N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FL33 776 86338 T358 I A P L A I S T T G R G S S G
Baker's Yeast Sacchar. cerevisiae P24279 971 107499 T432 T A S L A I A T T G R G S S G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.5 86 N.A. 92.9 93.3 N.A. N.A. 81.4 80.1 75.9 N.A. 62.5 62.7 30.8 N.A.
Protein Similarity: 100 99.8 100 87.2 N.A. 96.6 97 N.A. N.A. 92 90.7 88.1 N.A. 80 78.6 49.5 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 86.6 100 100 N.A. 100 100 20 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 100 100 N.A. 100 100 46.6 N.A.
Percent
Protein Identity: N.A. 47.6 N.A. 49.3 39.8 N.A.
Protein Similarity: N.A. 66 N.A. 68.1 54.7 N.A.
P-Site Identity: N.A. 13.3 N.A. 80 80 N.A.
P-Site Similarity: N.A. 13.3 N.A. 80 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 87 7 0 94 0 14 0 0 0 0 7 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 7 0 0 87 0 94 0 0 87 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 7 0 0 0 87 0 0 0 7 0 0 0 0 0 % I
% Lys: 0 0 0 7 0 7 0 0 0 0 0 0 0 0 0 % K
% Leu: 7 0 0 14 0 0 0 0 7 7 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % N
% Pro: 0 7 80 0 0 0 67 7 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 74 0 0 0 0 0 0 94 0 0 0 0 % R
% Ser: 0 0 14 0 7 0 14 0 7 0 0 0 94 87 0 % S
% Thr: 80 0 0 0 0 0 0 87 87 0 0 0 0 0 0 % T
% Val: 0 0 0 7 0 7 0 0 0 0 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _